Central apnoea after balanced general anaesthesia that included dexmedetomidine

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Central apnoea after balanced general anaesthesia that included dexmedetomidine.

Dexmedetomidine is an alpha(2)-adrenoreceptor agonist that, in spite of its potent sedative, amnesic, and analgesic properties, has minimal respiratory depressant effect. Even at doses adequate for general anaesthesia, it does not cause central apnoea. Thus, it has been claimed that "combining alpha(2)-agonists with opiate narcotics or non-steroidal anti-inflammatory drugs can enhance the analg...

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Risks of general anaesthesia in people with obstructive sleep apnoea.

These include: Data supplement http://bmj.com/cgi/content/full/329/7472/955/DC1 "Extra references" References http://bmj.com/cgi/content/full/329/7472/955#BIBL This article cites 29 articles, 8 of which can be accessed free at: Rapid responses http://bmj.com/cgi/eletter-submit/329/7472/955 You can respond to this article at: service Email alerting box at the top right corner of the article Rece...

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Effect of dexmedetomidine on postoperative cognitive dysfunction in elderly patients after general anaesthesia: A meta-analysis

Objective We undertook a meta-analysis to investigate the effect of dexmedetomidine on postoperative cognitive dysfunction (POCD). Methods We searched PubMed, EMBASE, the Cochrane Library, CNKI and Google Scholar to find randomized controlled trials (RCTs) of the influence of dexmedetomidine on POCD in elderly adults who had undergone general anaesthesia. Two researchers independently screened ...

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Effect of Intraoperative Dexmedetomidine Infusion on Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy under General Anaesthesia

Background: Post-operative nausea and vomiting (PONV) is the most frequently encountered complication after laparoscopic cholecystectomy.The evidence regarding the effect of dexmedetomidine in decreasing PONV is insufficient. The aim of this study was to evaluate the effect of dexmedetomidine infusion as an adjuvant to general anaesthesia on PONV after laparoscopic cholecystectomy. Methods: One...

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Anaesthesia and sleep apnoea.

Sleep disordered breathing is a common problem affecting all age groups, particularly in association with certain other medical conditions and syndromes. The pathological consequences of the disorder may be severe, with significant implications for the perioperative management of sufferers. Research into the effects of surgery and anaesthesia on sleep is very much in its infancy. Understanding ...

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ژورنال

عنوان ژورنال: British Journal of Anaesthesia

سال: 2005

ISSN: 0007-0912

DOI: 10.1093/bja/aei263